The role of early nutrition on the development of very low birth weight newborns

The role of early nutrition on metabolic markers and hormones, growth and neurocognitive development of very low birth weight newborns

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN64647571

Enrollment

120

Registered

2019-04-12

Start date

2018-05-31

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Growth and neurodevelopment of very low birth weight (<1500 g) newborns Pregnancy and Childbirth

Interventions

Cord blood sample for glucose, insulin, IGF-1, IGFBP-3, leptin, ghrelin, adiponectin and DNA extraction is drawn after birth of very low birthweight newborns. Daily nutritional data are evaluated, com

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Very low birth weight newborns (<1500g), both AGA and SGA, born in Kaunas Perinatal centre. 2. Parental consent acquired.

Exclusion criteria

Exclusion criteria: 1. Congenital malformations 2. Posthaemorrhagic hydrocephalus 3. Abdominal surgery resulting in part of the bowel resection

Design outcomes

Primary

Measure	Time frame
1. Growth restriction at discharge measured using Fenton growth charts 2. Body composition at discharge measured using DXA analysis.	—

Secondary

Measure	Time frame
1. At 12 months corrected gestational age neurodevelopment is assessed using Bayley II scale.	—

Countries

Lithuania

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Jun 11, 2026