Recurrent miscarriage Pregnancy and Childbirth
Conditions
Interventions
Part 1:
Women who had recurrent pregnancy loss (RPL) who have been prescribed heparin between 2011 and 2015 as part of their standard medical care have their medical notes reviewed. La
Sponsors
Changhua Christian Hospital
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Part 1: 1. Women of child-bearing age 2. Recurrent pregnancy loss 3. Treated with heparin as part of standard care between 2011 and 2015 Part 2: 1. Women of child-bearing age 2. Recurrent pregnancy loss 3. Protein S deficiency (both the free antigen and function of protein S were reduced)
Exclusion criteria
Exclusion criteria: 1. Allergic to heparin or other Low Molecular Weight Heparins 2. Problem with bruising or bleeding too easily 3. History of heparin-induced thrombocytopenia 4. Stroke 5. Recently had an operation on brain 6. Renal dysfunction
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Live birth rate is measured using the outcome of pregnancy at either abortion or live-births at the time of delivery collected from medical records. | — |
Secondary
| Measure | Time frame |
|---|---|
| Obstetric complication rate is measured using specific parameters such as the birth body weight (if it is low birth weight for gestational age, or appropriate for gestational age), the gestational age when delivery (if less than 28 weeks, between 28 and 36 weeks of gestation, or term pregnancy meaning delivered later than 36 complete weeks of gestation) at delivery collected from medical records. | — |
Countries
Taiwan
Outcome results
None listed