Prehabilitation of patients with colorectal cancer Cancer
Conditions
Interventions
A multimodal tele-prehabilitation intervention was embedded within the existing colorectal cancer pathway of VieCuri Medical Center. Therefore, no additional hospital visits were required for study pu
Sponsors
VieCuri Medisch Centrum
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Diagnosed with colorectal cancer (stage I, II, or III) requiring elective colorectal resection 2. =18 years of age 3. Undergoing elective colorectal resection at VieCuri Medical Center, Venlo 4. Have a score =7 metabolic equivalents of task (METs) on the veterans-specific activity questionnaire (VSAQ) 5. Have a baseline VAT =11 mL/min/kg or an VO2peak =18 mL/kg/min, as measured during the CPET 6. Sign written informed consent
Exclusion criteria
Exclusion criteria: 1. Not able to operate a mobile phone 2. Requiring acute (emergency) surgery 3. Contraindications for physical training of exercise testing as stated in the ATS/ACCP statement on cardiopulmonary exercise testing 4. Unable to cooperate with test procedures (e.g. physical complaints or insufficient knowledge of Dutch Language)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Feasibility outcomes: 1. Study participation rates will be measured by calculating the number of participating patients as a proportion of potentially eligible patients that were referred for prehabilitation. 2. Reasons for non-willingness to participate measured during a telephone interview with the patient before the start of the study. 3. Number and severity of adverse events related to the physical exercise training program measured based on self-report of the participants and will be registered by the physiotherapist in the study management system. 4. Exercise adherence will be monitored with the app of HC@home and will be assessed as 1) completion of the recommended number training sessions per week and 2) as the ability to achieve the prescribed intensity and duration of exercise sessions. Successful exercise adherence involves achieving >80% of the prescribed exercise duration, intensity, and frequency of the training sessions during the study period but will be considered for each parameter separately. 5. Drop-out rates were calculated as the number and proportion of participating patients that are lost to follow up during the tele-prehabilitation program (i.e., between final inclusion and follow-up measurement). Reasons for drop-outs are registered by the principal investigator . | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Participant experiences as measured by a patient appreciation questionnaire at the end of the tele-prehabilitation program (follow-up measurement 1 or 2 days before surgery) 2. User friendliness of the mobile phone application (HC@Home) that was used for tele-prehabilitation measured using the Systems Usability Questionnaire at the end of the tele-prehabilitation program (follow-up measurement 1 or 2 days before surgery) 3. Changes in physical fitness levels between baseline and follow up (approximately 4 weeks): 3.1 Change in aerobic fitness during teleprehabilitation, as measured by during the Constant Work rate test (CWT) 3.2 Change in functional performance, as measured by the 30-second chair stand test (30-sec CST) 3.3 Change in functional performance, as measured by the 4-meter gait speed (4-MGS) test | — |
Countries
Netherlands
Outcome results
None listed