Localization of transcranial magnetic stimulation in treatment of depression

Imaging-based optimization of repetitive transcranial magnetic stimulation for depression

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN63779759

Enrollment

Registered

2017-04-11

Start date

2016-05-01

Completion date

Unknown

Last updated

2024-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Major depression Mental and Behavioural Disorders Major depression

Interventions

The brain stimulation treatment and whole-head MRI is part of the normal clinical care of the patients. For the study purposes, location of the stimulating coil is registered to enable computation of

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Major depressive disorder in MINI interview 2. Aged 15-60 years

Exclusion criteria

Exclusion criteria: 1. Serious psychiatric or somatic illness 2. MRI/TMS contraindications

Design outcomes

Primary

Measure	Time frame
Depression severity is measured using the Montgomery-Åsberg Depression Rating Scale (MADRS) total at week 1 and 6.	—

Secondary

Measure	Time frame
1. Depression severity is measured using The Patient Health Questionnaire (PHQ-9) at week 1 and 6 2. Functioning is measured using Social and Occupational Functioning Assessment Scale (SOFAS) at week 1 and 6	—

Countries

Finland

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026