Sarcopenia Musculoskeletal Diseases Sarcopenia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged 65 years and over 2. Skeletal mass index less than 8.87kg/m2 and 6.42kg/m2
Exclusion criteria
Exclusion criteria: 1. Participants with metal implants 2. Severe heart problem 3. Neurodegenerative diseases 4. Peripheral vascular disease 5. Vestibular disorders 6. Severe osteoporosis with fractures within one year prior to the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Muscle mass (cross-sectional area of vastus medialis) was measured by ultrasound at baseline, 6 (18 training sessions), 12 (36 training sessions), 18 and 24 weeks 2. Muscle strength (peak torque of knee extension) was measured by Cybex with isokinetic (180 and 60 degrees per second) and isometric (knee flexed at 90 degrees) contractions at baseline, 6 (18 training sessions), 12 (36 training sessions), 18 and 24 weeks 3. Physical performance was measured by five-repetition sit-to-stand, timed-up-and-go test and 10-meter walking test at baseline, 6 (18 training sessions), 12 (36 training sessions), 18 and 24 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Proprioception was measured by knee joint repositioning test at baseline, 6 (18 training sessions), 12 (36 training sessions), 18 and 24 weeks 2. Balance was measured by tandem, one-leg stand with eyes open and closed at baseline, 6 (18 training sessions), 12 (36 training sessions), 18 and 24 weeks 3. Voluntary activation was measured by twitch interpolation test at baseline and 12 weeks (36 training sessions) | — |
Countries
Hong Kong