Inoperable non-small cell lung cancer Cancer Non small cell lung (NSCL)
Conditions
Interventions
Please note that recruitment to this trial was closed earlier than planned on the 7th December 2007 (initial anticipated end date of recruitment: 12th July 2008) due to poor accrual. 46 patients have
Sponsors
Medical Research Council (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Histologically or cytologically confirmed stage I-III NSCLC, considered suitable for chemotherapy and CHART 2. Inoperable disease as assessed by a lung cancer MDT with thoracic surgical input 3. Previously untreated by chemotherapy or radiotherapy 4. Eastern Cooperative Oncology Group (ECOG) performance status 0 or 1 5. No prior or current malignant disease likely to interfere with protocol treatment
Exclusion criteria
Exclusion criteria: 1. Medically unstable (e.g. unstable diabetes, uncontrolled arterial hypertension, infection, hypercalcaemia or ischaemic heart disease 2. Previous or current malignant disease likely to interfere with protocol or comparisons 3. Women who are pregnant or lactating 4. Women of childbearing potential who are not practising adequate contraceptive precautions
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Overall survival | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Progession-free survival 2. Response 3. Toxicity 4. Quality of Life 5. Tumour Control 6. Cost effectiveness | — |
Countries
United Kingdom
Outcome results
None listed