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Studying how muscles, ligaments and connective tissues around the knee work in healthy people using vibration testing, body composition analysis and muscle activity sensors

Assessment of the repeatability and agreement of myotonometry in measuring the biomechanical properties of myofascial–ligamentous structures: comparison with muscle bioelectrical activity and bioimpedance in the knee region – a prospective observational study (MYOFLEX)

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN63017711
Enrollment
110
Registered
2026-03-06
Start date
2025-06-11
Completion date
Unknown
Last updated
2026-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy volunteers Other

Interventions

The planned study is exploratory in nature and focuses on the non-invasive assessment of biomechanical, bioelectrical, and bioimpedance properties of myo-ligamentous-fascial structures in the region o

Sponsors

Wroclaw Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 24 Years

Inclusion criteria

Inclusion criteria: 1. Age between 20 and 24 years 2. Informed and voluntary consent to participate confirmed by signing a consent form 3. No serious cardiovascular or respiratory diseases in acute phase 4. No implanted electrical devices such as pacemakers or defibrillators 5. No acute musculoskeletal injuries

Exclusion criteria

Exclusion criteria: 1. Lack of consent to participate in the study 2. Age outside the range of 20–24 years 3. Severe musculoskeletal 4. Infections or exacerbation of chronic diseases 5. Recent muscle injury at measurement site 6. Implanted pacemaker or other active electronic device 7. Pregnancy in women 8. Extensive skin lesions preventing attachment of EMG electrodes 9. Inability to cooperate

Design outcomes

Primary

MeasureTime frame
1. Body mass, fat mass (kg and %), muscle mass (kg), hydration status (%), other relevant indices measured using bioelectrical impedance with Tanita analyzer at a single measurement during the study visit (baseline) 2. Muscle tone (frequency, Hz), stiffness (N/m), elasticity (dimensionless index), relaxation time (ms), creep (deformation time ratio) measured using MyotonPRO at rest and during isometric contraction during a single study visit 3. Amplitude and pattern of bioelectrical muscle activity (µV), background sEMG, response to functional tension measured using surface electromyography (sEMG) with disposable EMG electrodes at rest and during isometric contraction during a single study visit.

Secondary

MeasureTime frame
There are no secondary outcome measures

Countries

Poland

Contacts

Public ContactWeronika Bajer
weronika.bajer@umw.edu.pl+48 (0)71/784 28 15

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Apr 17, 2026