Nutritional support after esophagectomy Nutritional, Metabolic, Endocrine
Conditions
Interventions
Initially, patients were randomly allocated to receive one of the following:
1. MIE group: minimally invasive Ivor Lewis esophagectomy and home enteral nutrition. In this group, patien
the trial was therefore non-randomized.
Sponsors
Second Affiliated Hospital of Zhejiang University School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Diagnosed with esophageal and esophagogastric junction cancer 2. Deemed suitable for potentially curative resection with intrathoracic anastomosis
Exclusion criteria
Exclusion criteria: 1. Patients with unresectable tumors 2. Patient older than 80 years old 3. Patients that needed cervical incision and anastomosis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. The nutritional status, measured using the PG-SGA standard questionnaire, BMI, Albumin and Hemoglobin within 3 days prior to surgery, 2 weeks and 3 months after operation 2. Quality of life, measured using the European Organization for Research and Treatment of Cancer (EORCT) general quality of life questionnaire (QLQ-C30) within 3 days prior to surgery, 2 weeks and 3 months after operation | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Outcomes for different surgical procedures , measured using the total hospital stay, time in the ICU, morbidity and mortality within 30 days 2. Pain after surgery, measured using visual analogue score (VAS) until day 3 after surgery 3. Complications after surgery, measured using pneumonia, chylothorax, vocal-cord paralysis, wound infection needing reoperation, anastomotic leakages, cardiac insufficiency, ileus need stop enteral nutrition and jejunostomy site enterocutaneous fistula 4. Pathological results, measured using pathological tumor-node-metastasis classification, resection and circumferential margins and the number of lymph nodes retrieved | — |
Countries
China
Outcome results
None listed