Ultrasound guided foam sclerotherapy combined with sapheno-femoral ligation compared to surgical treatment of varicose veins

Randomised contolled trial of ultrasound guided foam sclerotherapy combined with sapheno-femoral ligation compared to surgical treatment of varicose veins

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN62966817

Enrollment

Registered

2011-04-20

Start date

2003-07-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic venous insufficiency Circulatory System Varicose veins

Interventions

Group surgery: 1. High saphenofemoral ligation 2. Strip to the knee 3. Multiple phlebectomies Group surgery and foam: High saphenofemoral ligation under local anaesthesia and foam sclerotherapy u

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Primary symptomatic varicose veins involving the great saphenous system in patients whom had had no previous treatment for varicose veins and who were suitable for day case surgery

Exclusion criteria

Exclusion criteria: 1. Primary varicosities involving the short saphenous vein 2. Patients with previous surgery or sclerotherapy for varicose veins 3. Previous deep vein thrombosis (DVT) 4. Risk factors for DVT 5. Coagulopathy 6. Peripheral vascular disease 7. Known allergy to anaesthetic or sclerosing agents 8. Previous iatrogenic allergic reaction 9. Malignancy 10. Pregnancy

Design outcomes

Primary

Measure	Time frame
1. Patient recovery period 2. Quality of life Outcome measured up to 7 years maximum	—

Secondary

Measure	Time frame
1. Frequency of complications 2. Cost of the treatment Outcome measured up to 7 years maximum	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026