HIV and iron deficiency Infections and Infestations Unspecified human immunodeficiency virus [HIV] disease
Conditions
Interventions
The participants will be randomly allocated to the following arms:
Arm 1: Supplementation of oral multi-vitamins with iron, (3 mg/kg body weight/day) for 3 months
Arm 2: Oral multi-vitamins alone for
Sponsors
Liverpool School of Tropical Medicine (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Both males and females, age 6-59 months 2. Presence of moderate anaemia (haemoglobin 7-9.9 g/dl) 3. HIV positive 4. Mean corpuscular volume (MCV) <=73 f/l (for children from 2-5 years); <=67 f/l (for children <2 years) 5. Informed consent by parent/guardian
Exclusion criteria
Exclusion criteria: 1. Patients already on nutritional supplements 2. Presence of gross congenital, cognitive or neuro-developmental anomalies 3. Children with malnutrition requiring supplementary feeding; weight-for-height less than 80% of expected; presence of bipedal oedema 4. Patients with haemoglobin =10 g/dl
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of all-cause sick visits during the trial and follow up period. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Incidence of all-cause hospitalisations during the trial and follow up period 2. Incidence of haemoglobin <7 g/dl during the follow up period of 6 months 3. Laboratory diagnosis of acquired immune deficiency syndrome (AIDS) or clinical stage IV disease, patient requiring highly active antiretroviral treatment (HAART) | — |
Countries
Malawi
Outcome results
None listed