Chronic obstructive pulmonary disease Respiratory
Conditions
Interventions
Assessment of socio-demographic status, co-morbidities and medications will be obtained through self-report measures. Assessment of lung health and lung function will occur, including spirometry. Nutr
participants will be asked to wear the device for 7 consecutive days during waking hours and removed during water-based activities.
Sponsors
University of Leicester
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients: 1. Aged =18 years 2. Physician diagnosis of COPD 3. Spirometry confirmed COPD, based on GOLD criteria, with FEV1/FVC <0.7, and FEV1<80% predicted 4. Medical Research Council (MRC) dyspnoea score grade 2 or higher Healthy controls: 1. Aged =18 years 2. No physician diagnosis of chronic respiratory disease
Exclusion criteria
Exclusion criteria: 1. Co-morbidities such as severe or unstable cardiovascular, other internal diseases and locomotor difficulties that preclude exercise 2. Malignant disease or other serious illness which will interfere with participation in the PR programme 3. Unable or unwilling to provide informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Assessed at the research visit which is scheduled to occur only once: 1. Exercise capacity measured by the ISWT and lung function assessed through spirometry 2. Nutritional and dietary status assessed using measures of height, weight, body composition (bioelectrical impedance), mid-upper arm circumference and 7-day diet diary 3. Physical activity levels measured using accelerometers | — |
Secondary
| Measure | Time frame |
|---|---|
| Assessed at the research visit which is scheduled to occur only once: 1. Anxiety and depression level measured using Hospital Anxiety and Depression Scale (HADS) 2. Breathlessness measured using Medical Research Council (MRC) Dyspnea scale 3. Health status measured using COPD Assessment Test (CAT) and Clinical COPD Questionnaire (CCQ) 4. Economic impact measured using Work Productivity and Activity impairment (WPAI) Questionnaire 5. Strength, measured by 5x sit-to-stand test | — |
Countries
Sri Lanka
Contacts
Public ContactMark Orme
Outcome results
None listed