Streamlining cross-sectional imaging pathways (SCIPs)

Streamlining cross-sectional imaging pathways (SCIPs): A feasibility and economic modelling study of point of care creatinine testing in radiology

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN62796844

Enrollment

300

Registered

2017-04-04

Start date

2017-02-15

Completion date

Unknown

Last updated

2019-05-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Specialty: Renal disorders, Primary sub-specialty: Renal disorders

Interventions

The intervention is a PoC creatinine test and a standard laboratory renal function blood test performed at the initial visit (CT scan appointment), this will take 5 minutes. This whole blood sample is

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients attending for contrast-enhanced CT scan 2. Age over 18 3. Non-pregnant patients 4. Able to consent

Exclusion criteria

Exclusion criteria: 1. Patients undergoing a non-contrast CT scan or other radiology test 2. Patients under 18 years 3. Pregnant patients 4. Those unable to provide written consent

Design outcomes

Primary

Measure	Time frame
Renal function concordance measured as the difference between the serum creatinine value from PoCT and laboratory analysis at initial visit.	—

Secondary

Measure	Time frame
1. Recruitment rate recorded as the number of eligible participants who consented to participate in the study at initial visit 2. Attrition rate recorded as the number of participants that return for follow up blood test at 2-3 days post-contrast administration 3. Failure rate recorded as the number of test analyses which do not produce a result from PoC and laboratory tests at initial and follow up visits 4. Screening questionnaire effectiveness measured as the number of patients with no risk factors who have a reduced renal function identified (eGFR <40) at initial visit 5. Renal function recorded as the concordance between serum creatinine and eGFR from the pre-scan result obtained within 3 months of scan and the renal function at initial visit 6. Rate of contrast-induced acute kidney injury (CI-AKI) recorded as the number of participants who have a =25% rise in serum creatinine on follow up blood test 2-3 days post-contrast administration	—

Measure

Time frame

1. Recruitment rate recorded as the number of eligible participants who consented to participate in the study at initial visit 2. Attrition rate recorded as the number of participants that return for follow up blood test at 2-3 days post-contrast administration 3. Failure rate recorded as the number of test analyses which do not produce a result from PoC and laboratory tests at initial and follow up visits 4. Screening questionnaire effectiveness measured as the number of patients with no risk factors who have a reduced renal function identified (eGFR <40) at initial visit 5. Renal function recorded as the concordance between serum creatinine and eGFR from the pre-scan result obtained within 3 months of scan and the renal function at initial visit 6. Rate of contrast-induced acute kidney injury (CI-AKI) recorded as the number of participants who have a =25% rise in serum creatinine on follow up blood test 2-3 days post-contrast administration

—

Countries

United Kingdom

Contacts

Public ContactMartine Harris

martine.harris@midyorks.nhs.uk+44 1924 542297

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026