Acute coronary syndrome Circulatory System
Conditions
Interventions
Sex steroids (E2, total testosterone [T]) and DHEA-S, oxidized low-density lipoproteins, high-sensitive C-reactive protein (CRP), white blood cell counts (WBC), and cardiac enzymes (creatine kinase [C
Sponsors
Medical University of Sofia
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Adult men and women admitted to hospital with acute coronary syndrome.
Exclusion criteria
Exclusion criteria: Acute infectious disease, any diagnosed neoplastic disease; fracture, physical trauma or surgical procedure a month before and after the inclusion period and at the end of the follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Oxidized low-density lipoproteins (oxLDL), high-sensitive C-reactive protein (hsCRP), white blood cell counts (WBC), and cardiac enzymes (creatine kinase [CK], Muscle-Brain fraction of CK [CPK-MB], high-sensitive troponin T [hsTnT]) were evaluated in plasma obtained within two hours of coronary angiography (CAG) 2. Coronary disease severity, measured using SYNTAX score after CAG 3. Total 17ß-estradiol [E2], total testosterone [T], dehydroepiandrosterone-sulfate [DHEA-S] measured using blood samples drawn 48 hours after symptom onset | — |
Secondary
| Measure | Time frame |
|---|---|
| Patient information on obesity, diabetes mellitus and incidence of revascularizations, reinfarctions and deaths after one- year follow up measured using patient records. | — |
Countries
Bulgaria
Contacts
Public ContactNiya Semerdzhieva
Outcome results
None listed