Association between cardiovascular risk and moderate-severe obstructive sleep apnea in Chile

Prevalence of cardiovascular comorbidities and association with different subtypes of Chilean patients with moderate-severe Obstructive Sleep Apnea in Santiago (SantOSA)

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN62293645

Enrollment

3000

Registered

2019-07-24

Start date

2009-08-01

Completion date

Unknown

Last updated

2023-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obstructive sleep apnea Nervous System Diseases Sleep apnoea

Interventions

The researchers developed a prospective cohort study of participants aged >18 years since 2009 who were prospectively included to date in a single tertiary center. They will include all participants w

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Participants aged >18 years 2. Referred for the sleep study because of the clinical suspicion of OSA (snoring symptoms, apneas observed by bed partner or excessive daytime sleepiness or major cardiovascular comorbidities)

Exclusion criteria

Exclusion criteria: 1. Participants with other sleep disorders such as periodic limb movements of sleep (PLMS), NREM and arousal, REM and hypoxia, arousal and poor sleep 2. Participants who refuse to sign the consent form

Design outcomes

Primary

Measure	Time frame
1. All-cause mortality measured through a review of the national register database (https://www.registrocivil.cl) at 3, 5 and 10 years 2. Cardiovascular mortality measured through a review of the national register database (https://www.registrocivil.cl) at 3, 5 and 10 years	—

Secondary

Measure	Time frame
1. New onset of hypertension measured by either medical record or telephone consultation at 5 and 10 years 2. New onset of T2DM measured by either medical record or telephone consultation at 5 and 10 years 3. New onset of CHD measured by either medical record or telephone consultation at 5 and 10 years 4. New onset of atrial fibrillation measured by either medical record or telephone consultation at 5 and 10 years	—

Measure

Time frame

1. New onset of hypertension measured by either medical record or telephone consultation at 5 and 10 years 2. New onset of T2DM measured by either medical record or telephone consultation at 5 and 10 years 3. New onset of CHD measured by either medical record or telephone consultation at 5 and 10 years 4. New onset of atrial fibrillation measured by either medical record or telephone consultation at 5 and 10 years

—

Countries

Chile

Contacts

Public ContactJorge Jorquera

jjorquera@clinicalascondes.cl+56 (0)992896812

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 27, 2026