Breast cancer Cancer Malignant neoplasm of breast
Conditions
Interventions
Radiotherapy using v_DIBH: Patients will receive their radiotherapy using the v_DIBH technique
Study Entry : Registration only
Sponsors
Royal Marsden NHS Foundation Trust (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Women or men with left-sided breast cancer 2. Recommendation for whole breast or chest wall RT within FAST-Forward trial 3. Patients with any heart tissue in a tangential RT field placed according to standard anatomical borders 3. Any breast volume 4. Eastern Cooperative Oncology Group (ECOG) performance status <=1 5. Patients able to tolerate breath-hold
Exclusion criteria
Exclusion criteria: 1. Right-sided breast cancer 2. Ineligible for whole breast or chest wall RT within FAST-Forward trial 3. Patients with micro- or macro-scopic disease on sentinel node biopsy who have not undergone completion axillary node clearance 4. Previous radiotherapy to any region above the diaphragm
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Percentage of patients in whom a reduction in mean LAD dose (Gy) is achieved with v_DIBH measured at end of study | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Costs of techniques (equipment and time to scan/treat) measured at end of study 2. Difference in mean doses (Gy) to heart, ipsilateral lung and whole lungs, and maximum LAD dose measured at end of study 3. Interfraction reproducibility of patient position measured at end of study 4. Patient and radiographer satisfaction with positioning technique (questionnaire) measured at end of study. 5. Proportion of patients in whom prone position would have been optimal measured at end of study 6. Time spent in various activities / stages of treatment planning and delivery measured at end of study | — |
Countries
United Kingdom
Outcome results
None listed