Therapy of frequent relapsing, steroid-sensitive nephrotic syndrome in childhood: efficacy of mycophenolate mofetil versus cyclosporin A

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN61976169

Enrollment

Registered

2006-05-26

Start date

2004-01-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Idiopathic nephrotic syndrome Urological and Genital Diseases Nephrotic syndrome

Interventions

Immunosuppressive therapy with MMF versus cyclosporin A.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Children aged 3 - 17 years 2. Frequent relapses of steroid-sensitive nephrotic syndrome, associated with minimal changes on renal biopsy 3. Glomerular Filtration Rate (GFR) greater than 70 ml/min

Exclusion criteria

Exclusion criteria: 1. Other histological findings on renal biopsy 2. Other severe concomittant diseases 3. Decreased GFR

Design outcomes

Primary

Measure	Time frame
Number of relapses during the observation period	—

Secondary

Measure	Time frame
Decrease in GFR, hypertension and hyperlipidemia during the observation period	—

Countries

Germany

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026