End-stage renal disease treated with hemodialysis. Urological and Genital Diseases End-stage renal disease
Conditions
Interventions
Participants were randomised into 4 groups:
1. Current dialysis with atorvastatin (10 mg orally per day during the whole follow-up periode [24 months])
2. Dialysis usin
Sponsors
Ministry of Science, Education and Sport of the Republic of Croatia
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: End-stage renal diasese on maintenance hemodialysis lasting at least 3 months.
Exclusion criteria
Exclusion criteria: 1. Previously transplanted 2. Previously treated with peritoneal dialysis 3. History of active infection in the last 3 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Patient survival with or without MIA syndrome at 2 years 2. Survival of patient with MIA syndrome according to randomisation/intervention at 2 years | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Determinantion of independent predictors of mortality in MIA syndrome patients at 2 years 2. Influence of intervention on laboratory parameters of MIA syndrome at 2 years 3. Safety assessement of atorvastatin application, checked after 1, 3, 6, 12 and 24 months according to known precautions for statin use 4. Hospitalisations rate and frequency of patients with or without MIA syndrome at 2 years | — |
Countries
Croatia
Outcome results
None listed