Chronic obstructive pulmonary disease (COPD) Respiratory
Conditions
Interventions
Data collection:
1. At inclusion: patient demographics, COPD history, comorbidities, medications, vaccinations, and clinical data at AE onset
2. During hospitalization: patient pathway, treatments, IC
3 years – vital status and cause of death
Analysis:
Data will be analyzed using R software. Descriptive statistics, comparisons between groups, and methods to identify AE subtypes will be applied. Su
Sponsors
Collège des Pneumologues des Hôpitaux Généraux (CPHG)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Age =18 years 2. All patients hospitalized in a pulmonology department for an acute exacerbation (AE) of COPD, whether previously diagnosed or newly identified, admitted between 01/11/2025 and 31/10/2026, regardless of: 2.1. Mode of admission (emergency, outpatient consultation, direct admission, intensive care unit, other department), or 2.2. Associated conditions (e.g., obstructive sleep apnoea/hypopnoea syndrome [OSAHS], obesity-hypoventilation syndrome, etc) Also eligible: 1. Patients with decompensation initially admitted to pulmonology and subsequently transferred to intensive care 2. Patients already receiving ventilatory support (long-term oxygen therapy, non-invasive ventilation) 3. Patients for whom COPD is diagnosed as a result of the index AE Patient information sheet provided and explained; oral consent or absence of objection obtained.
Exclusion criteria
Exclusion criteria: 1. Age <18 years 2. Previous inclusion in the study 3. Patients unable to perform pulmonary function tests, cooperate with the protocol, or respond to questions 4. Patients deprived of liberty following a judicial or administrative decision 5. Patients unable to give consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 3-year survival of patients hospitalized for acute exacerbations (AE) of COPD, along with the predictive factors associated with this survival, measured using the patient’s vital status at 3 years | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. 3-month survival of patients hospitalized for acute exacerbations (AE) of COPD, along with the predictive factors associated with this survival, measured using the patient’s vital status at 1 year 2. Existence of subtypes of exacerbations, defined by the presence of (at the time of patient inclusion): 2.1. Comorbidities (asthma, history of Pseudomonas aeruginosa infection, presence of alpha-1 antitrypsin deficiency, respiratory allergies, bronchiectasis, emphysema, gastroesophageal reflux, stroke, dyslipidemia, ischemic heart disease, peripheral artery disease (PAD), heart failure, cardiac arrhythmias, hypertension (high blood pressure), osteoporosis, diabetes, lung cancer) 2.2. Biological values 3. The characteristics of patients, COPD, and its management prior to hospitalization in patients with COPD admitted to hospital for exacerbations, defined by: 3.1. Patient characteristics: sex, age, height, weight, smoking status 3.2. Management prior to hospitalization: previously diagnosed COPD, medically followed for COPD, prior treatments 4. The hospitalization management of COPD exacerbations, assessed during the patient’s hospital stay for the exacerbation (that led to inclusion), using the following criteria: mode of admission to the department, management of the exacerbation in critical care, treatments administered during hospitalization, discharge procedures, and treatments prescribed at discharge. 5. The evolution of patient characteristics, COPD, and its management since 2006, assessed by comparing the data collected at inclusion in the 2006 EA-BPCO study with those collected at inclusion in the 2025/2026 study. 6. The seasonality of COPD exacerbations, assessed based on the number of patients included in the study across the four seasons of the year 7. The impact of social deprivation on 3-year survival of patients admitted to hospital for acute exacerbations, assessed by combining the social deprivation score at inclusion with the patients’ vital status | — |
Countries
France
Contacts
Public ContactNicolas Delberghe
Outcome results
None listed