Bilateral impaction of mandibular third molars Oral Health
Conditions
Interventions
Randomization:
The two mandibular surgical sites were randomly assigned to one of two materials for application within the socket: Group A (left side: gelatin sponge, right side: bisphosphonates-loade
Sponsors
Damascus University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients aged between 18 and 30 years 2. Symmetrically positioned, non-impacted mandibular third molars requiring surgical extraction in the same patient 3. Medically healthy patients with no systemic diseases 4. Patients who have provided informed consent to participate in the study
Exclusion criteria
Exclusion criteria: 1. Patients with syndromic conditions 2. Allergy to any of the medications used in the study 3. Presence of localized lesions or acute infections in the third molar region 4. Patients with a history of radiotherapy for tumors in the head and neck region 5. Patients taking medications that affect bone metabolism 6. Presence of temporomandibular joint (TMJ) disorders, such as condylar dislocation or displacement 7. Patients with poor oral hygiene 8. Pregnant or breastfeeding women 9. Smokers and alcohol consumers 10. Non-cooperative patients 11. A time discrepancy exceeding 10 minutes between extractions on both sides
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Pain intensity measured using the Visual Analog Scale (VAS) on days 1, 3, and 7 post-surgery 2. Facial edema measured using the Tape Method on baseline and days 2 and 5 post-surgery 3. Radiographic healing and bone density assessment measured using cone-beam computed tomography (CBCT) scans immediately after the surgical extraction and 2 months post-surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| The degree of clinical healing measured using the Landry Healing Index on days 3 and 7 post-surgery | — |
Countries
Syria
Contacts
Public ContactMustafa Jaweesh
Outcome results
None listed