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Investigation of the sensitivity of hypothalmic dopamine receptors using amisulpiride in healthy young men

Investigation of the sensitivity of hypothalmic dopamine receptors using amisulpiride in healthy young men

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN61805353
Enrollment
20
Registered
2003-09-12
Start date
2002-12-19
Completion date
Unknown
Last updated
2016-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mental and Behavioural Disorders: Psychosis Mental and Behavioural Disorders Psychosis

Interventions

20 Healthy male subjects will be recruited. After undergoing a general health screen, and having had the study explained to them and given informed consent, subjects will be asked to complete the foll

Sponsors

Department of Health (UK)
Lead Sponsor

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: A total of 20 male subjects aged 18-30, will be recruited from the population of the University. All subjects will be healthy non-smokers. Posters advertising the study will be displayed around the University of Birmingham and individuals expressing an interest in the study will be given a subject information sheet and have the study explained to them by one of the investigators. Suitable subjects wishing to participate in the study will complete a general health questionnaire and sign a consent form. It will be made clear that subjects are free to withdraw from the study at any time.

Exclusion criteria

Exclusion criteria: 1. Volunteer suffers from cardiovascular disease 2. Volunteer has/is suffering from an infection or is on medication 3. Volunteer has asthma 4. Volunteer has epilepsy or a predisposing condition 5. Volunteer has a history of kidney disease 6. Volunteer has a history of Parkinson's disease In addition to the health questionnaire, volunteers will undergo an independent medical screening with Professor MJ Kendall before entering the study to ensure that there are no underlying general health problems or psychological reasons that contraindicates a neuroendocrine challenge with amisulpiride.

Design outcomes

Primary

MeasureTime frame
Not provided at time of registration

Secondary

MeasureTime frame
Not provided at time of registration

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026