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Effect of exercises combined with education and self-management skills on patients with knee osteoarthritis (OA)

The effect of Combining knee and hip Exercises on the Load in Knee OsteoArthritis: a pilot study (CELKOA)

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN61720526
Enrollment
20
Registered
2013-07-22
Start date
2011-04-25
Completion date
Unknown
Last updated
2020-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee osteoarthritis (degeneration of the knee joint) Musculoskeletal Diseases Gonarthrosis [arthrosis of knee]

Interventions

Participants attended a six-week group exercise programme once a week in the church hall at The Avenue Methodist Church in Sale. It was delivered by the investigator, a physiotherapist, and a physioth

Sponsors

University of Salford (UK)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Participants diagnosed with medial knee OA either clinically or radiographically by a consultant/GP and meeting the American College of Rheumatology (ACR) criteria for knee OA (Altman, 1987) 2. 40 years or older 3. Able to walk for at least 100 metres. 4. Speak and understand English as the patients needed to understand the patient information sheet and the consent forms, which were written in English. The educational materials and patient reported measures were also in English. As a pilot study, there was not sufficient funding to translate these into other languages.

Exclusion criteria

Exclusion criteria: 1. Diagnosis of patellofemoral or lateral knee OA more than medial 2. Currently wearing a brace or insoles 3. Currently using cane or other assistive devices to help mobility 4. Severe cognitive, cardio-respiratory, musculoskeletal or neurological problems other than knee OA 5. Taking medications that would limit participation in the exercise programme and/or assessments 6. A history of high tibial osteotomy or other realignment surgery or total knee replacement. The effect of a conservative intervention (i.e. exercises) on loading is under investigation and these interventions change the loading on the knee and are considered the last choice of treatment with knee OA. 7. Corticosteroid injection in the knee in the last three months to ensure it does not interfere with the results of the exercise programme, as it has short-term effect on pain (Bellamy et al., 2006) 8. Current participation in other treatment programmes that might affect the results of this pilot study, such as other exercise programmes, manual therapy, or acupuncture 9. Gross ligament instability

Design outcomes

Primary

MeasureTime frame
External knee adduction moment (EKAM): the EKAM was assessed during gait. It was also assessed in single leg stance (SLS). This is referred to as single leg stance knee adduction moment (SSKAM). Additionally, knee adduction angular impulse (KAAI) during gait was assessed.

Secondary

MeasureTime frame
1. Hip, knee, and ankle kinematics and kinetics in the coronal and sagittal planes and temporo-spatial parameters: some of these measures include: speed, stance time, step length, and the external hip adduction moment. 2. Muscle strength: all isokinetic and isometric testing were performed using the Biodex system 3 isokinetic dynamometer (Biodex Medical Systems, Shirley, N.Y., USA). The strength of the knee flexors and extensors was assessed concentrically at 60°/s and isometrically at 45°. The hip abductors were assessed isometrically at 0°. 3. Dynamic balance: a modified Star Excursion Balance Test (SEBT) was used to assess dynamic balance. 4. Muscle co-contraction: surface electromyography (EMG) data were collected using a Noraxon Telemyo system (www.noraxon.com) at a sampling rate of 3000Hz. Eight channels were used to record average activation with electrodes placed on the right and left vastus lateralis (VL), vastus medialis (VM), biceps femoris (BF), and semitendinosus (ST) muscles. 5. Knee injury and Osteoarthritis Outcome Score (KOOS) f6. Arthritis self-efficacy questionnaire 7. Medical Outcomes Study 12-item Short-Form Health Survey (SF-12v2) 8. Adherence

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026