Acute ischemic stroke after intravenous thrombolysis Circulatory System
Conditions
Interventions
Patients will be randomized using the research randomizer to either the treatment group or the control group. The research randomizer (randomizer.org) is a free online software used to generate random
Sponsors
Baguio General Hospital and Medical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. >18 years old 2. Having an acute ischemic stroke within 4.5 hours post-ictus, moderate to severe stroke with NIHSS 10-25 on admission 3. Meets criteria for intravenous thrombolysis
Exclusion criteria
Exclusion criteria: 1. Hemorrhagic strokes on baseline CT scan 2. History of hepatic failure 3. History of chronic kidney disease (creatinine clearance <30) 4. Stroke mimickers
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Degree of independence or disability measured using the Modified Rankin Scale (MRS) at discharge and 3 months | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Symptomatic ICH assessed using CT scan at baseline (admission), 24 hours and 5 days 2. Degree of cognitive dysfunction measured using the Montreal Cognitive Assessment (MoCA) test at 3 months 3. Degree of stroke severity measured using the National Institutes of Health Stroke Scale, or NIH Stroke Scale (NIHSS) at baseline (admission), 24 hours, discharge and 3 months | — |
Countries
Philippines
Contacts
Public ContactPeter Allan Quitasol
Outcome results
None listed