Effects of evidence-based exercise on body composition, physical fitness, and recovery-related parameters in Hematopoietic Stem Cell Transplantation Patients

Effects of evidence-based exercise on body composition, physical fitness, and recovery-related parameters in Hematopoietic Stem Cell Transplantation Patients: A randomized controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN61498391

Enrollment

Registered

2017-04-03

Start date

2017-03-16

Completion date

Unknown

Last updated

2020-10-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hematopoietic Stem Cell Transplantation Patients Cancer Hematopoietic Stem Cell Transplantation Patients

Interventions

Participants are randomly allocated to either the exercise group or to the control group. Randomisation is done using stratified randomisation according to gender and transplanting. E

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients with leukemia, lymphoma, or multiple myeloma who are scheduled to receive autologousor allogeneic HSCT 2. Aged between 18 and 65 years 3. Ability to understand and provide written informed consent in Korea 4. No evidence of cardiac or pulmonary failure associated with treatment 5. Ability to conduct low and moderate intensity exercise program

Exclusion criteria

Exclusion criteria: 1. Existing evidence of recurrent or metastatic disease 2. Pregnant or planned to be pregnant within six month 3. Any condition unsuitable for participation in the study

Design outcomes

Primary

Measure	Time frame
1. Body composition (muscle mass) is measured using the BIA machine (Inbody IH-U070R, Biospace, Korea) at baseline and after entering a bio-clean room, and discharge from hospital 2. Physical fitness is measured using the six min-walking test (or 2 minute walking), step test, hand-grip strength, sit and reach, 8 foot up and go test, and chair stand at baseline and after entering a bio-clean room, and discharge from hospital	—

Measure

Time frame

1. Body composition (muscle mass) is measured using the BIA machine (Inbody IH-U070R, Biospace, Korea) at baseline and after entering a bio-clean room, and discharge from hospital 2. Physical fitness is measured using the six min-walking test (or 2 minute walking), step test, hand-grip strength, sit and reach, 8 foot up and go test, and chair stand at baseline and after entering a bio-clean room, and discharge from hospital

—

Secondary

Measure	Time frame
Current secondary outcome measures as of 08/04/2019: 1. Time to platelet engraftment is measured using hospital charts daily during hospital stay 2. Absolute neutrophil count is measured using hospital charts daily during hospital stay 3. Amount of blood transfusion is measured using hospital charts daily during hospital stay 4. Length of hospital stay is measured using hospital charts daily during hospital stay 5. Symptoms are measured using the Korean version of the M. D. Anderson symptom inventory (MDASI) at baseline and after entering a bio-clean room, and discharge from hospital Previous secondary outcome measures: 1. Time to platelet engraftment is measured using hospital charts daily during hospital stay 2. Absolute neutrophil count is measured using hospital charts daily during hospital stay 3. Amount of blood transfusion is measured using hospital charts daily during hospital stay 4. Amount of meal intake is measured using hospital charts daily during hospital stay 5. Length of hospital stay is measured using hospital charts daily during hospital stay 6. Symptoms are measured using the Korean version of the M. D. Anderson symptom inventory (MDASI) at baseline and after entering a bio-clean room, and discharge from hospital 7. Satisfaction in exercise program is measured using Satisfaction with Life Scale (SLS) at discharge from hospital	—

Measure

Time frame

Current secondary outcome measures as of 08/04/2019: 1. Time to platelet engraftment is measured using hospital charts daily during hospital stay 2. Absolute neutrophil count is measured using hospital charts daily during hospital stay 3. Amount of blood transfusion is measured using hospital charts daily during hospital stay 4. Length of hospital stay is measured using hospital charts daily during hospital stay 5. Symptoms are measured using the Korean version of the M. D. Anderson symptom inventory (MDASI) at baseline and after entering a bio-clean room, and discharge from hospital Previous secondary outcome measures: 1. Time to platelet engraftment is measured using hospital charts daily during hospital stay 2. Absolute neutrophil count is measured using hospital charts daily during hospital stay 3. Amount of blood transfusion is measured using hospital charts daily during hospital stay 4. Amount of meal intake is measured using hospital charts daily during hospital stay 5. Length of hospital stay is measured using hospital charts daily during hospital stay 6. Symptoms are measured using the Korean version of the M. D. Anderson symptom inventory (MDASI) at baseline and after entering a bio-clean room, and discharge from hospital 7. Satisfaction in exercise program is measured using Satisfaction with Life Scale (SLS) at discharge from hospital

—

Countries

Korea, South

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 17, 2026