Detection of chronic thromboembolic pulmonary hypertension (CTEPH) following pulmonary embolism

Multicentre observational screenINg survey for the detection of chronic thromboembolic PUlmonary hyperTensiON (CTEPH) following Pulmonary Embolism

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN61417303

Enrollment

1000

Registered

2009-06-29

Start date

2009-05-18

Completion date

Unknown

Last updated

2019-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary embolism/chronic thromboembolic pulmonary hypertension Circulatory System Pulmonary embolism

Interventions

Patients with confirmed pulmonary embolism are followed up by regular telephone contacts at 6, 12 and 24 months using a standardised dyspnoea questionnaire. If the questionnaire discovers previously u

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Men and women (no age limitations) with pulmonary embolism within the preceding 4 weeks, demonstrated by: 1. Pulmonary angiography, or 2. Contrast enhanced spiral computed tomography, or 3. High probability lung scintigraphy (perfusion and ventilation imaging)

Exclusion criteria

Exclusion criteria: 1. Confirmed diagnosis of pulmonary arterial hypertension (PAH) or CTEPH before inclusion 2. Pre-existing severe chronic dyspnoea (New York Heart Association [NYHA] grade III or IV) due to other reasons than PE 3. Cancer or other life-threatening disease with a life expectancy less than 6 months

Design outcomes

Primary

Measure	Time frame
Amount of patients who develop symptomatic CTEPH at 6, 12 and 24 months after PE.	—

Secondary

Measure	Time frame
1. Comparison of collected baseline data of the patients who developed CTEPH with the baseline data of the patients who did not develop CTEPH within the 2-year period after diagnosis of PE to identify any potential risk factors 2. Comparison of the results of the dyspnoea questionnaire answered by telephone with the dyspnoea evaluation by the investigator at the clinic to test the usefulness of the telephone screening algorithm in medical practice for diagnosing CTEPH after PE	—

Measure

Time frame

1. Comparison of collected baseline data of the patients who developed CTEPH with the baseline data of the patients who did not develop CTEPH within the 2-year period after diagnosis of PE to identify any potential risk factors 2. Comparison of the results of the dyspnoea questionnaire answered by telephone with the dyspnoea evaluation by the investigator at the clinic to test the usefulness of the telephone screening algorithm in medical practice for diagnosing CTEPH after PE

—

Countries

Switzerland

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 24, 2026