Pain in split skin graft donor sites Surgery Complications of procedures, not elsewhere classified
Conditions
Interventions
A prospective, randomised controlled trial was performed. The self-adhesive fabric dressing Mefix® (Mölnlycke Health Care Ltd) was used as a control and compared to fibrin glue spray (Tisseel®, Baxter
Sponsors
Guy?s and St Thomas? NHS Foundation Trust (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. 18 years old and over 2. Conscious during post operative period 3. Small to moderate area of split skin graft (SSG) procedure necessary 4. Lateral thigh SSG donor site preferable
Exclusion criteria
Exclusion criteria: 1. Hypersensitivity to beef or beef products ((Tisseel® is produced from bovine aprotonin) 2. Those requiring thicker grafts, greater than 8/1000 inch 3. Thigh donor sites unavailable. Back and buttocks can be used as donor sites in certain cases, they may have a different pain profile 4. Known immunodeficiency will have an effect on healing 5. Mental incapacity to consent or undertake questionnaire 6. Concurrently participating in another clinical trial and having received another investigational drug or device within the last 30 days to avoid confounding factors 7. Alternative source of severe distracting pain which may down score donor site pain
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Daily pain and disability scores from day 1 to 14 post-operatively using a Visual Analogue Scale | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Length of hospital stay 2. Duration of requirement for dressings | — |
Countries
United Kingdom
Outcome results
None listed