Prematurity Neonatal Diseases Prematurity
Conditions
Interventions
Harp music vs quiet room. The infants allocated to the intervention group had harp music for 45 minutes each day for 3 days.
Sponsors
National Institutes of Health, National Center for Complementary and Alternative Medicine (USA)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Infants hospitalized at Brenner Children's Hospital Neonatal Intensive Care or Intermediate Care UnitsInfants were eligible if they satisfied the following criteria: 1. Born between 25 and 36 weeks gestational age 2. At least 34 weeks gestational age by the time of enrollment 3. Had been medically stable in the intermediate care nursery for at least three days 4. Had passed the neonatal hearing screen 5. Slept in a crib rather than an isolette 6. Took full oral feedings 7. Free of apnea and bradycardia spells 8. Expected to remain in the intermediate nursery for at least seven more days to achieve stable body temperature
Exclusion criteria
Exclusion criteria: 1. Any medical condition known to adversely affect either: 1.1. Central nervous system (e.g. intraventricular hemorrhage of Grade II or higher) 1.2. Cardiac or adrenal function (e.g. major cardiac anomaly) 1.3. Movement (e.g. spasticity, hypotonia, or fractured clavicle) 2. Any ongoing need for stressful or invasive medical procedures or steroid medications
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Salivary cortisol was measured just prior to harp music/quiet/usual care observation period and just after each day 2. HRV was measured during the intervention each day 3. Activity was measured during and after the intervention each day 4. Weight, meausred at baseline (Monday) and 5 days (Friday) | — |
Secondary
| Measure | Time frame |
|---|---|
| Growth, measured as weight gain at 5 days (this trial is 5 days long). | — |
Countries
United States of America
Outcome results
None listed