Effect of plant sterol margarines on serum cholesterol in everyday practice

An open randomised trial of the effect of plant sterol margarines on serum cholesterol in everyday practice

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN61150880

Enrollment

232

Registered

2009-03-31

Start date

2003-09-01

Completion date

Unknown

Last updated

2017-10-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypercholesterolaemia in adults Circulatory System Disorders of lipoprotein metabolism and other lipidaemias

Interventions

Polyunsaturated margarine or sterol enriched margarine taken for 6 weeks with a crossover design (no washout period). Total duration of interventions and follow-up: 12 weeks

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Adult (both males and females) over 18 with cholesterol >6 mmol

Exclusion criteria

Exclusion criteria: Those considered unsuitable by their GP e.g., cancer, acute or chronic psychotic disorder or dementia

Design outcomes

Primary

Measure	Time frame
Serum cholesterol and beta-carotene assessed at baseline, 6 and 12 weeks	—

Secondary

Measure	Time frame
High-density lipoprotein (HDL) cholesterol, total cholesterol (TC)/HDL ratio, assessed at baseline, 6 and 12 weeks	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026