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CML IV - Chronic phase chronic myeloid leukaemia/CML 2000

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN61147621
Enrollment
800
Registered
2000-10-25
Start date
1996-01-01
Completion date
Unknown
Last updated
2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Leukaemia Cancer Chronic myeloid leukaemia

Interventions

Cycle of chemotherapy and an autograft with subsequent IFN/IFN therapy alone

Sponsors

Medical Research Council (MRC) (UK)
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. The interval from diagnosis to registration does not exceed 3 months (if received only hydroxyurea in these 3 months proceed to register, if alpha Interferon (IFN) has been given contact co-ordinators) 2. They are aged 18-60; they have newly diagnosed CML 3. They have acceptable criteria for chronic phase 4. They have given informed consent and are willing to be randomised, there is no contraindication to collection of blood or marrow progenitor cells before treatment is commenced 5. They are not pregnant

Exclusion criteria

Exclusion criteria: Not provided at time of registration

Design outcomes

Primary

MeasureTime frame
Length of survival, quality of life, cytogenetic response

Secondary

MeasureTime frame
Not provided at time of registration

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026