Ulcerative colitis Digestive System Ulcerative colitis
Conditions
Interventions
Biopsies were taken during colonoscopy from patients with quiescent UC with endoscopical MH (Mayo score = 1). All biopsies were reassessed by three blinded pathologists using the Gupta, Riley and Gebo
Sponsors
Radboud University Medical Center (Netherlands)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. A colonoscopic examination between January 2014 and July 2015 2. A well-established diagnosis of UC according to clinical and histological criteria 3. Endoscopic mucosal healing throughout the entire colon according to Mayo (=1) 4. Randomly taken colonic biopsy specimens in both left and right colon with a clear description of the microscopic features by the pathologist
Exclusion criteria
Exclusion criteria: 1. Mayo endoscopic score > 1 2. Diagnosed with either Crohn’s disease or indeterminate colitis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intra- and inter-observer variability all histological indices | — |
Secondary
| Measure | Time frame |
|---|---|
| The relationship with endoscopic mucosal healing, and the relationship between the initial judgment of the primary pathologist in all scoring systems | — |
Countries
Netherlands
Outcome results
None listed