Seasonal rhinitis Ear, Nose and Throat Seasonal rhinitis
Conditions
Interventions
Patients randomised to receive two injections out of hay fever season, either EPD or placebo.
Sponsors
NHS R&D Regional Programme Register - Department of Health (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. To be recruited from GP lists aged 18 - 64 years 2. Either sex 3. History of seasonal allergic rhinitis extending mid-May to end-July 4. Positive skin prick test to mixed grass pollens
Exclusion criteria
Exclusion criteria: 1. Symptoms of sufficient severity to require regular treatment outside usual grass-pollinating season 2. History of predominant seasonal problem not corresponding with usual grass-pollinating season 3. Rhinitis complicated by nasal infection, rhino-sinusitis, nasal polyps, septal deviation, gross turbinate hypertrophy or intranasal mass 4. History of anaphylaxis or laryngeal oedema 5. Undergoing nasal surgery within 2 months 6. Receiving specific immunotherapy (high dose method) within preceeding 12 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Measured during 12 week hay fever season: number of problem free days and post-treatment symptom scores. | — |
Secondary
| Measure | Time frame |
|---|---|
| No secondary outcome measures | — |
Countries
United Kingdom
Outcome results
None listed