Prevalence of exercise-induced laryngeal obstruction (EILO) in athletes Respiratory
Conditions
Interventions
Participants undergo a clinical examination by the study physician, dynamic spirometry, eucapnic voluntary hyperventilation test, skin prick test, and continuous laryngoscopy during exercise test (CLE
Sponsors
Umeå University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Competitive athlete ( i.e. not at recreational level) 2. Age 15-35 years
Exclusion criteria
Exclusion criteria: 1. Pregnancy 2. FEV1 200 systolic or >100 diastolic at rest 4. Aortic aneurysm 5. Previous heart attack or stroke
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Prevalence and natural history of exercise-induced laryngeal obstruction (EILO), defined as laryngeal obstruction at glottic or supraglottic level using a visual scoring system, assessed with continuous laryngoscopy during exercise test (CLE), at the first and second visit (summer or winter season) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Current asthma, defined as a) physician-diagnosed asthma, and b) use of asthma medication in the last 12 months, evaluated by questionnaire at first visit 2. Bronchial hyperreactivity, defined as 10% decrease in FEV1 after EVH test, measured at the first and second visit (summer or winter season) 3. Allergy, defined as a) reaction with >2 mm wheal to skin prick test, and b) self-reported allergic symptoms, measured at first visit | — |
Countries
Sweden
Outcome results
None listed