Continuous TAP blocks for major gynaecological surgery

A double blind, randomized, controlled study to assess the efficacy of continuous transversus abdominis plane (TAP) blocks for analgesia and enhanced recovery following major gynaecological surgery

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN60295543

Enrollment

Registered

2016-06-23

Start date

2016-08-11

Completion date

Unknown

Last updated

2021-03-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain after major gynaecological oncology surgery Cancer

Interventions

This is a single centre randomised controlled study investigating the effects of bilateral transversus abdominis blockade on post-operative analgesic requirement after major gynaecological surgery. It

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Patients aged 30-75 undergoing elective gynaecological oncology surgery

Exclusion criteria

Exclusion criteria: 1. Patients unable to give informed consent (mainly language difficulty) 2. Patients with contraindications to drugs specified in the protocol or participation in another medical trial involving medications

Design outcomes

Primary

Measure	Time frame
Morphine use via a PCA pump. The amount used will be recorded daily but the primary outcome will be the amount used up to 0800hr on Day 3 (after which the lidocaine infusion will be stopped)	—

Secondary

Measure	Time frame
1. Pain score: Patients will be asked for their pain score (none, mild, moderate or severe) every morning at rest, on taking a deep breath, and on coughing 2. Morphine side effects: Episodes of nausea and vomiting over the last 24 hours will be recorded daily. The day of the first post-operative bowel action will be noted 3. Respiratory function: Peak expiratory flow rate will be recorded pre-operatively and daily from post-operative day 1 4. Operative and clinical outcomes data, including the extent of the abdominal incisions and the duration of hospital stay 5. Adverse events will also be recorded	—

Measure

Time frame

1. Pain score: Patients will be asked for their pain score (none, mild, moderate or severe) every morning at rest, on taking a deep breath, and on coughing 2. Morphine side effects: Episodes of nausea and vomiting over the last 24 hours will be recorded daily. The day of the first post-operative bowel action will be noted 3. Respiratory function: Peak expiratory flow rate will be recorded pre-operatively and daily from post-operative day 1 4. Operative and clinical outcomes data, including the extent of the abdominal incisions and the duration of hospital stay 5. Adverse events will also be recorded

—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026