Investigation of leukocyte trafficking into skin blisters during cardiopulmonary bypass

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN60289857

Enrollment

Registered

2006-07-10

Start date

2004-01-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ischaemic heart disease Circulatory System Ischaemic heart disease

Interventions

Coronary artery bypass surgery, with or without cardiopulmonary bypass, with or without use of aprotinin infusion

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Primary, elective, coronary artery bypass surgical patients, between ages 45-75 years

Exclusion criteria

Exclusion criteria: 1. Pregnancy 2. Myocardial infarction in previous six weeks 3. On steroid medication 4. Malignancy 5. Chronic inflammatory disorder

Design outcomes

Primary

Measure	Time frame
1. Leukocyte trafficking into skin blisters - total and differential count 2. Measurement of inflammatory mediators within blister fluid	—

Secondary

Measure	Time frame
Cellular phenotype within blister fluid - activation markers on cell surface	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026