Early detection of cardiovascular dysfunction and health behaviours in the young with type 2 diabetes

Early detection of cardiovascular dysfunction and health behaviours in the young with type 2 diabetes: an observational study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN60207691

Enrollment

Registered

2011-12-23

Start date

2009-10-05

Completion date

Unknown

Last updated

2016-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 diabetes Nutritional, Metabolic, Endocrine Type 2 diabetes

Interventions

Description: 20 young people (aged 18 ? 30) with T2DM, 10 age matched controls and 10 age and BMI matched controls. The study involves two visits. Visit one data on anthropometric, demographic and ps

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Aged 18-30 2. Type 2 diabetes 3. Either male or female

Exclusion criteria

Exclusion criteria: 1. Estimated glomerular filtartion rate (eGFR) < 60mls/min 2. Asthma 3. Body weight more than or equal to 150kg 4. Contraindication to magnetic resonance imaging (MRI)

Design outcomes

Primary

Measure	Time frame
1. Lifestyle change 2. Depression 3. Illness beliefs 4. Weight 5. Cardiovascular diseases (CVD) risk	—

Secondary

Measure	Time frame
1. Cardiac MRI and echocardiogram data 2. Maximal oxygen consumption (VO2) max 3. Physical activity measured by accelerometer 4. Inflammatory biomarkers: IL-6, TNF alpha, IL6 receptor, hsCRP 5. Biochemical outcomes: HbA1c, glucose, insulin, c-peptide, vitamin D, U&E, LFTs, TFTs 6. Psychological variables measured through questionnaire and semi-structured interviews 7. Anthropometric variables: Body mass index (BMI), waist circumference, blood pressure	—

Measure

Time frame

1. Cardiac MRI and echocardiogram data 2. Maximal oxygen consumption (VO2) max 3. Physical activity measured by accelerometer 4. Inflammatory biomarkers: IL-6, TNF alpha, IL6 receptor, hsCRP 5. Biochemical outcomes: HbA1c, glucose, insulin, c-peptide, vitamin D, U&E, LFTs, TFTs 6. Psychological variables measured through questionnaire and semi-structured interviews 7. Anthropometric variables: Body mass index (BMI), waist circumference, blood pressure

—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026