Alveolar ridge preservation Oral Health
Conditions
Interventions
Informed consent will be obtained by investigators participating in the study, and cases will be diagnosed clinically and radiographically to ensure the matching of inclusion criteria. On the day of s
Sponsors
Damascus University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Current inclusion criteria as of 13/02/2025: 1. Patients with a single rooted tooth in the maxillary arch who had a treatment plan of extraction and alveolar ridge preservation with no evidence of acute infection such as severe swelling, suppuration, abscess, and/or spontaneous bleeding, and the teeth adjacent to the tooth to be extracted must be present 2. At least 18 years old 3. Non-smoker 4. Participants treated for periodontal disease 5. Participants that show the presence of buccal plate at the extraction site as determined by a sectional cone-beam computed tomography (CBCT) scan. If the patient qualified based on the CBCT scan 6. Participants with excellent oral health (20% or less of plaque index) 7. Participants with 2 mm at least of keratinized tissue at the surgical site _____ Previous inclusion criteria: 1. Patients with a single rooted tooth in the maxillary arch who had a treatment plan of extraction and alveolar ridge preservation with no evidence of acute infection such as severe swelling, suppuration, abscess, and/or spontaneous bleeding, and the teeth adjacent to the tooth to be extracted must be present 2. At least 18 years old 3. Participants smoke fewer than 10 cigarettes per day 4. Participants treated for periodontal disease 5. Participants that show the presence of buccal plate at the extraction site as determined by a sectional cone-beam computed tomography (CBCT) scan. If the patient qualified based on the CBCT scan 6. Participants with excellent oral health (20% or less of plaque index) 7. Participants with 2 mm at least of keratinized tissue at the surgical site
Exclusion criteria
Exclusion criteria: 1. Lactating or pregnant female 2. Medical conditions that are contraindicated with periodontal surgery 3. Use anticoagulant drugs or steroids 4. Bleeding disorders 5. Autoimmune or immune proliferative disorders 6. Acute inflammation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Current primary outcome measure as of 24/03/2025: 1. Width of Alveolar Ridge: Superimposition between pre-treatment and 4-month post-intervention CBCT images was performed using Ondemand 3D software The measurements were conducted at three levels (4, 7, and 10 mm). _____ Previous primary outcome measure as of 13/02/2025: 1. Width of Alveolar Ridge: Superimposition between pre-treatment and 4-month post-intervention CBCT images was performed using Ondemand 3D software. A pre-fabricated stent was not used for this purpose. The measurements were conducted at three levels (4, 7, and 10 mm). 2. Vertical Height to the Buccal and Palatal Alveolar Bone: Superimposition between pre-treatment and 4-month post-intervention CBCT images was performed using Ondemand 3D software to measure vertical resorption on the buccal and palatal sides. A pre-fabricated stent was not used for this purpose. 3. Radiographic Bone Density: Radiographic bone density was measured after 4 months using EZ-3D Plus software for CBCT analysis. The entire socket area was evaluated using the "Region of Interest" feature. A pre-fabricated stent was not used for this purpose. _____ Previous primary outcome measure: 1. Width of alveolar ridge: at three levels (4, 7, and 10 mm), the distance between the two horizontal buccal and palatal points located at the same level. Measured using a pre-fabricated stent before extraction and 4 months after the alveolar ridge preservation. 2. Vertical height to the buccal and palatal alveolar bone: the distance between the buccal/palatal crest to the vertical point, measured using a pre-fabricated stent before extraction and 4 months after the alveolar ridge preservation. 3. Thickness of the buccal (BPT) and palatal/lingual (PPT) alveolar plates: measured using a pre-fabricated stent at the first sectional CBCT scan (before extraction). 4. Radiographic bone density: at three levels (4,7, and 10 mm), the mean density values in the three levels are taken, measure | — |
Secondary
| Measure | Time frame |
|---|---|
| Current secondary outcome measures as of 24/03/2025: 1. Vertical Height to the Buccal and Palatal Alveolar Bone: Superimposition between pre-treatment and 4-month post-intervention CBCT images was performed using Ondemand 3D software to measure vertical resorption on the buccal and palatal sides. 2. Radiographic Bone Density: Radiographic bone density was measured after 4 months using Ondemand 3D software for CBCT analysis. 3. Wound healing recorded using the Landry Wound Healing Index weekly during the first month after the alveolar ridge preservation 4. Pain measured using visual analog scale (VAS) and the number of analgesics, recorded daily during the first week after the alveolar ridge preservation 5. Complications after tooth extraction, recorded (if present) as soon as the patient reports it. 6. Periodontal Probing Depth (PPD) and Gingival Recession (GR): Measured before extraction and at 4 months post-extraction using a UNC-15 periodontal probe at the extraction site and the adjacent mesial and distal teeth. 7. Keratinized Tissue Width (KTW): Measured using a UNC-15 periodontal probe from the gingival margin to the mucogingival junction (MGJ) at the extraction site, before extraction and at 4 months post-extraction. _____ Previous secondary outcome measures as of 14/02/2025: 1. Wound healing and complete wound epithelization recorded using the Landry Wound Healing Index weekly during the first month after the alveolar ridge preservation 2. Pain measured using visual analog scale (VAS) and the number of analgesics, recorded daily during the first week after the alveolar ridge preservation 3. Complications after tooth extraction, recorded (if present) as soon as the patient reports it. _____ Previous secondary outcome measures: 1. Wound healing recorded using the Landry Wound Healing Index weekly during the first month after the alveolar ridge preservation 2. Complete wound epithelization recorded by application of toluidine blue weekly during the fir | — |
Countries
Syria
Contacts
Public ContactEmad Aldden Aldemmari
Outcome results
None listed