Perceived stress and stress-related symptoms (sleep disturbance, abdominal symptoms, common cold symptoms). Mental and Behavioural Disorders
Conditions
Interventions
This is an observational cohort study (specifically, with a short-term prospective cohort) without therapeutic procedures in office workers. Venous blood samples and saliva samples are collected for b
Sponsors
Yakult Honsha European Research Center for Microbiology VOF
Eligibility
Sex/Gender
All
Age
20 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. A female or male participant, aged 20 to 65 years inclusive at the time of screening 2. Healthy office workers as defined in the below definition: 2.1. An individual who has continuously lived in Europe for at least the past five years. 2.2. An individual who works a minimum of 4 days per week and commutes to the office at least 3 days per week (excluding those whose home is considered their office). 2.3. Individuals with reduced working hours, are eligible if they work at least 60% of full time hours. (For instance, an individual in the following scenario would be accepted: Monday and Tuesday – full days, Wednesday and Thursday – half days, and working in the office on Monday, Tuesday, and Wednesday.) 2.4. An individual who is deemed to spend more than half of their working hours each day engaged in desk work. 2.5. Individuals working night shifts are excluded from the study. Only those who work day shifts are considered eligible to participate. 3. Willing and capable to complete a daily electronic diary during the 6-week study period.
Exclusion criteria
Exclusion criteria: 1. High IPAQ activity level at screening. 2. Known difficulty providing saliva and blood samples. 3. Participant suffering from pollinosis, chronic rhinitis or asthma. 4. Participant suffering from active periodontitis or gingivitis 5. Participant being an active smoker/ vaper at the time of the Screening visit or actively smoking/ vaping in the past six months (more than 5 cigarettes per day). 6. Females of child-bearing potential who are pregnant or planning to become pregnant during the study duration. 7. History of a diagnosed mental illness or sleep disorders. 8. Participant suffering from serious liver, kidney, lung or gut diseases (excluding Irritable Bowel Syndrome (IBS)). 9. Receiving current medical treatment, except if stable (at the discretion of the investigator) on the medication for at least the past six months. 10. Regularly consuming probiotics or fermented milk (more than twice a week) 11. Taking drugs or supplements within the past three months that might affect the outcome of the study, such as anti-depressants, anti-psychotics, anti-anxiety medications, anti-insomnia medication, corticosteroids (including topical), melatonin, St. John’s Wort, anti-histamines, and tryptophan. 12. History of influenza vaccination or infection within the past month, or the plan to be vaccinated during this study. 13. Being deemed ineligible for this study by a physician, based on blood pressure, pulse rate, or other reasons.
Countries
Belgium
Contacts
Public ContactKazunori Suda
Outcome results
None listed