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Central venous pressure variation

Central venous pressure variation: a prospective interventional study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN60025937
Enrollment
20
Registered
2015-06-24
Start date
2006-05-01
Completion date
Unknown
Last updated
2021-05-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative mechanically ventilated cardiac surgery patients Circulatory System

Interventions

Stroke volume variation and pulse pressure variation were measured with pulse contour analysis using an arterial catheter, while central venous pressure variation was obtained from a central venous ca

Sponsors

Department of Intensive Care Medicine, Leiden University Medical Center
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Elective cardiac surgery patients postoperatively on the Intensive Care Unit who are mechanically ventilated with tidal volumes of 8-10 mL/kg without spontaneous breathing efforts or cardiac arrhythmia.

Exclusion criteria

Exclusion criteria: 1. Previous myocardial infarction 2. Congestive heart failure 3. Extensive peripheral arterial occlusive disease 4. Severe arrhythmia 5. Use of a cardiac assist device 6. Artificial pacing, postoperative valvular insufficiency or presence of spontaneous breathing during mechanical ventilation

Design outcomes

Primary

MeasureTime frame
Correlation, sensitivity and specificity of central venous pressure variation in the prediction of fluid responsiveness.

Secondary

MeasureTime frame
Accuracy of central venous pressure variation in comparison to stroke volume variation and pulse pressure variation.

Countries

Netherlands

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026