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Management of uncertainty in general practice using a rational evidence-based medicine (EBM) tool

Management of uncertainty through the rational use of EBM tools: the GEPURE study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN59998398
Enrollment
50
Registered
2026-07-21
Start date
2026-11-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Using the Ebmfrance evidence-based decision support tool in routine general practice for 12 months reduces physicians’ perceived diagnostic and therapeutic uncertainty and increases their decision confidence in real-life clinical situations. Other

Interventions

Study design Multicentre, mixed-methods, before-and-after, non-randomized study conducted in primary care among volunteer general practitioners. It combines a longitudinal quantitative component using
64 participants will be targeted, taking into account an expected response rate of 80% Recruitment Recruitment will be carried out among volunteer general practitioners, via dissemination through un

Sponsors

Société Française de Médecine Générale (SFMG)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
25 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. General practitioner or GP resident in active practice 2. Willing to participate in the study 3. Using or agreeing to use EBMFrance during the follow-up period

Exclusion criteria

Exclusion criteria: 1. Specialist physician other than general practice 2. Refusal to participate 3. Inability to use the digital tools required for data collection

Design outcomes

Primary

MeasureTime frame
Change in perceived uncertainty score before and after using the Ebmfrance tool measured using the Physicians’ Reaction to Uncertainty Scale (PRU), at baseline at inclusion and the end of the 12 month follow-up

Secondary

MeasureTime frame
Perceived complexity score measured using a Likert scale at each use of Ebmfrance;Decision Confidence Score measured using a questionnaire at before and after use of EBMFrance;Frequency and modalities of use of EBMFrance measured using the frequency of use, timing of use (during individual consultations vs during GAP meetings), and duration of each use at each use of Ebmfrance;Number and nature of changes in medical decisions per clinical case after using Ebmfrance measured using number and nature of changes (diagnosis, treatment, referrals) collected via a questionnaire at after use of the tool;Acceptability of the tool measured using the proportion of GPs who adhere to the study, dropout rate, mean time to perform an information search, reasons for failed information searches, qualitative data on perceived usefulness, strengths and limitations, and practicality of the tool at each use of Ebmfrance;Satisfaction of general practitioners with the tool measured using a Likert scale at each use of Ebmfrance

Countries

France

Contacts

Public ContactRachel;Julien Collignon-Portes;Le Breton

;

r.collignon-portes@wanadoo.fr;j.le.breton.com@gmail.com+33 618481583;+33 664009107

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Aug 10, 2026