Chronic periodontitis (CP)
Conditions
Interventions
Patients with CP were divided into two groups: CKD patients and controls
Both groups received instructions on oral hygiene techniques, including the manual techniques of tooth and interproximal brushi
Sponsors
Federal University of Juiz de Fora (Universidade Federal de Juiz de Fora [UFJF]) (Brazil)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients with CP, allocated to one of two groups depending on CKD status 1.1. CKD group: 1.1.1. Patients with CKD at stages 3 to 5 and undergoing conservative treatment 1.1.2. Recruited from the PREVENRIM, a CKD prevention clinic at the Interdisciplinary Nucleus of Studies, Research and Treatment in Nephrology (NIEPEN) of the Universidade Federal de Juiz de Fora (UFJF) 1.2. Control patients: 1.2.1. Patients with no systemic disease from the Periodontology Clinic of the School of Dentistry at UFJF 2. Over 18 years of age, either sex 2. Minimum of 20 natural teeth and without periapical lesions 3. Have received no periodontal, antimicrobial, or anti-inflammatory treatment within the last 6 months 4. Have not used steroids or immunosuppressant drugs within the last 6 months
Exclusion criteria
Exclusion criteria: 1. Pregnant or breast feeding women 2. Smokers or ex-smokers who had quit smoking within the last 10 years
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Inflammatory markers, assessed at baseline and 3 months post-PT 1. C-reactive protein (us-CRP) 2. Interleukin-6 (IL-6) 3. Prohepcidin | — |
Secondary
| Measure | Time frame |
|---|---|
| Biochemical analyses from blood sample in EDTA, at baseline and 3 months post-PT 1. Complete haemogram (automated Coulter STKS) 2. Serum iron (ferrozine) 3. Ferritin (electrochemiluminescence) 4. Transferrine saturation index (labtest ferrozine) | — |
Countries
Brazil
Outcome results
None listed