Total or a posterior partial fundoplication in the treatment of gastroesophageal reflux disease (GERD)

Total or a posterior partial fundoplication in the treatment of gastroesophageal reflux disease (GERD): results of a randomised trial after two decades of follow up

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN59614486

Enrollment

137

Registered

2011-03-10

Start date

1990-01-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastroesophageal reflux disease (GERD) Digestive System Gastroesophageal reflux disease (GERD)

Interventions

Surgery for GERD, total nissen or partial fundoplication. Please note that this is the follow-up for a RCT performed 20 years ago

the mean follow up has now reached 18 years. During these years 26% had died and 16% were unable to trace for follow up. Symptom outcomes were assessed by the use of validated self-reporting questionn

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Aged from 18 to 75 years, either sex 2. Established gastroesophageal reflux referred for surgical treatment in the beginning of 1990

Exclusion criteria

Exclusion criteria: 1. Pregnant 2. No possibility of compliance in the study protocol 3. Addict 4. Unable to understand the circumstances or the RCT information

Design outcomes

Primary

Measure	Time frame
1. Reflux control after 18 years 2. Side effects like gas bloat, dysphagia	—

Secondary

Measure	Time frame
Number of recurrences and reoperations	—

Countries

Sweden

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026