COVID-19 (SARS-CoV-2 infection) Infections and Infestations COVID-19 (SARS-CoV-2 infection)
Conditions
Interventions
1. Perform bedside fundal photography with or without optical coherence tomography on patients with COVID-19 at baseline and 4 week follow up
2. Assess tolerability of bedside fundal p
Sponsors
North Bristol NHS Trust
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Current inclusion criteria as of 28/09/2020: 1. Emergency Department or hospital admission for symptoms related to COVID-19 2. Aged =18 years or over, there is no upper age limit Previous inclusion criteria: 1. Emergency Department or hospital admission for symptoms related to COVID-19 2. Aged =18 years 3. Fluency in English
Exclusion criteria
Exclusion criteria: 1. COVID-19 patients receiving palliative care 2. Eye disease precluding fundoscopy 3. Significant agitation precluding safe practice of fundoscopy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Safety of performing the study measured using adverse events reported throughout the study 2. Tolerability of the study measured using a modified version of participant and clinician self-report intervention acceptability questionnaire at a single time | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Retinal vascular abnormalities will be quantified using proxy-Early Treatment Diabetic Retinopathy Study (ETDRS)/International Clinical Grading system grading of retinopathy and maculopathy and artificial intelligence software (e.g. EyeArt™) using fundal photography at baseline and 4 weeks 2. Macular and peripapillary retinal thickness and the thickness of the retinal layers will be analysed according to standard retinopathy parameters using optical coherence tomography data at baseline and 4 weeks (where available) | — |
Countries
United Kingdom
Contacts
Public ContactClaire Rice
Outcome results
None listed