Haemodynamic stress response during tracheal extubation Circulatory System
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. ASA Grade-I and Grade-II patients, age 20-55 years, weight 40-75 kg 2. Patients undergoing surgery under General Anaesthesia, who will be extubated at the end of surgery
Exclusion criteria
Exclusion criteria: 1. Patients with an allergy to study drugs 2. Patients with ASA grade 3 or more 3. Patients taking any adrenergic or psychotropic drugs 4. Patients with hepatic or renal disease 5. Patients with lung disease such as COPD
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| SBP, DBP, MAP and HR measured using a blood pressure cuff at baseline, at the time of intervention, 5, 10, and 15 minutes post-intervention | — |
Secondary
| Measure | Time frame |
|---|---|
| SBP, DBP, MAP and HR measured before giving the drug using a blood pressure cuff, at the time of intervention, 5, 10 and 15 minutes post-intervention in both parallel study groups | — |
Countries
India