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The BioVent - BIOmarkers for mechanically VENTilated patients cohort study

Prospective, multicentric, longitudinal study to determine predictors of outcome in mechanically ventilated critically ill patients

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN59376582
Enrollment
1000
Registered
2013-10-31
Start date
2011-04-01
Completion date
Unknown
Last updated
2023-05-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Critically ill patients on invasive mechanical ventilation Respiratory

Interventions

Visit day 0: assessment of baseline characteristics, vitals, venous puncture, subjective estimation of outcome Visit day 2: vitals, venous puncture, subjective estimation of outcome Visit day 4: vital

Sponsors

University Hospital of Basel
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Critically ill patients at the start of invasive mechanical ventilation 2. Estimated to require continuous ventilatory support for longer than 24 hours or if already ventilated for 12 to maximal 36 hours. 3. 18 years of age or older

Exclusion criteria

Exclusion criteria: 1. Pregnancy 2. Patients with pre-existing mental disorder precluding proper informed consent

Design outcomes

Primary

MeasureTime frame
Crude mortality within 28 days

Secondary

MeasureTime frame
1. Mortality within one year 2. Duration of ICU and hospital stay 3. Duration of mechanical ventilation, ventilation free days, weaning attempts, survival in the subgroups of mechanically ventilated patients, events during mechanical ventilation Endpoints will be obtained during ICU stay or at scheduled assessments.

Countries

Austria, France, Switzerland

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 14, 2026