Elective surgery with orotracheal intubation Surgery Elective surgery with orotracheal intubation
Conditions
Interventions
Participants undergoing elective surgery are randomly allocated to one of three groups. Randomisation is done by an independent person using a draw. The following groups are:
Group K1: Participants i
Sponsors
University Clinical Centre Maribor
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Aged 18-80 years 2. ASA Physical Status I or II 3. Elective surgery with orotracheal intubation
Exclusion criteria
Exclusion criteria: 1. Allergy or sensitivity to any medication used in trial 2. Alcohol or drug abuse 3. Chronical use of benzodiazepins, opiats or psyhothrophic medication 4. Body mass index higher than 35 or lower than 15 5. Anticipated difficult intubation (Mallampati III or IV) 6. Untreated arterial hypertension 7. Patients with Alzheimers, epilepsy or psychosis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Cardiac output is measured noninvasively using transthoracal electric bioimpedance every minute for first 16 minutes after induction of anesthesia 2. Blood pressure is measured noninvasively using arm cuffs every 2 minutes for first 16 minutes after induction of anesthesia 3. Heart rate is measured by ECG every minute for first 16 minutes after induction of anesthesia | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Bispectral index (BIS) (depth of sedation or anaesthesia) is monitored with 15 seconds sampling using forehead electrodes every minute for first 16 minutes after induction of anesthesia. 2. Dose titrated to clinical effect (loss of palpebral effect) | — |
Countries
Slovenia
Contacts
Public ContactDomen Kogler
Outcome results
None listed