Intrauterine adhesion Urological and Genital Diseases
Conditions
Sponsors
Sheng Jing Hospital
Shenyang Engineering Technology R&D Center of Cell Therapy Co., Ltd
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Moderate to severe intrauterine adhesion (AFS score =5) 2. No previous history of hysteroscopic adhesiolysis 3. Written consent obtained 4. Agreement to have second-look hysteroscopy 5. All the participants should be =18 years and younger than 40 years old
Exclusion criteria
Exclusion criteria: 1. Pregnancy or breastfeeding women 2. Minimal adhesion(AFS<5) 3. Previous history of hysteroscopic adhesiolysis 4. Highly allergic constitution or a history of severe allergic to thrombin 5. Systemic infection or severe local infection 6. Amenorrhea due to ovarian hypofunction or other causes 7. Severe cardiopulmonary disease, liver and kidney dysfunction and other severe underlying disease 8. Poor compliance (cannot finish the trial) or the investigator believes that the patient is not appropriate for treatment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The severity and extent of intrauterine adhesions scored according to a classification system recommended by the American Fertility Society (AFS) (1988 version), measured 2 months after surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| Pregnancy rates measured using ultrasound after the operation until 1 year after the termination of the clinical trial | — |
Countries
China
Contacts
Public ContactYutong Ge
Outcome results
None listed