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NO BLEeding excess with antiplatelet treatment with thromboserin during coronary artery bypass grafting (CABG)

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN59071456
Enrollment
120
Registered
2010-07-30
Start date
2009-01-01
Completion date
Unknown
Last updated
2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Topic: Cardiovascular

Interventions

Placebo or thromboserin 10 mg stat followed by 5 mg bd. Total duration of 12 months. Please note, this trial never started as the objectives were no longer viable.

Sponsors

Imperial College London (UK)
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: The original protocol, which received ethical and MHRA approval states. All patients requiring cardiac surgery.

Exclusion criteria

Exclusion criteria: The original protocol, which received ethical and MHRA approval states. Patients with bradycardia or bradyarrhythmia, unless drug induced and the drug stopped (e.g. ß- adrenoreceptor antagonists). Patients treated with serotonin re-uptake inhibitors.

Design outcomes

Primary

MeasureTime frame
Platelet aggregate and thrombus growth

Secondary

MeasureTime frame
Not provided at time of registration

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026