Addiction Mental and Behavioural Disorders
Conditions
Interventions
At each site, two or three community pharmacies dispensing and supervising oral methadone to patients will be recruited. Three drug services will be randomised to deliver one of the following three in
Sponsors
Kings College London & South London & Maudsley NHS Foundation Trust
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Aged > 18 years 2. Presenting to participating drug services for a new episode of opiate substitution treatment (OST) (patients must not have been receiving a prescription for methadone or other opiate substitution medication for >4 weeks and excludes those who have been transferred in from another service or prison) 3. Prescribed oral methadone 4. Receiving their supervised oral methadone at the local community pharmacy six days a week 5. Receiving supervised consumption of oral methadone from participating pharmacies 6. Owns a mobile phone 7. Willing and able to provide informed consent. Therefore, they must be able to read English and not require the service of an interpreter.
Exclusion criteria
Exclusion criteria: 1. Cannot read English AND would require the service of an interpreter to understand a brief oral description of the study 2. Already entered the trial. 3. Previously attended the service (drug clinic) and were discharged within the last three weeks
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Recruitment rate measured by number of patients recruited each week (of those entering opiate substitution treatment) over the 12-week recruitment period. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Feasibility outcomes 1.1 Rate of patients who are eligible and consent measured by percentage of screened patients who are eligible for inclusion in the feasibility trial and percentage of eligible patients who consent to participate. Data from Screening logs and Eligibility logs 1.2 Adherence to telephone text message system measured by percentage of matches between (a) daily pharmacy record and (b) record of attendance and medication compliance recorded on web-based telephone system. Data from daily pharmacy dispensing records and electronic database generated by software (this will record, due date, prescribed drug, doses and whether the patient missed their dose). 1.3 Percentage responding yes to 12 × weekly text message sent by researchers asking if they received all text message incentives or reminders for previous week (this will indicate whether they have mobile telephone and whether they are receiving text messages). Data from weekly text message received from participant 1.4 Accuracy of attendance measurement measured by percentage of matches between (a) daily pharmacy dispensing record and (b) record of attendance and medication compliance recorded in web-based software system. A ‘match’ is defined as agreement between (a) and (b) as to whether a participant attended their supervised methadone replacement appointment on a given day. Data from daily pharmacy dispensing records and electronic database generated by software (this will record, due date, prescribed drug, doses and whether the patient missed their dose. 1.5 Rates of follow-up measured by number and percentage of participants followed-up for research interview at 12 weeks post enrolment, by arm. Data from number of interviews conducted at 12 weeks post enrolment 1.6 The willingness of clusters (drug clinics and pharmacies) to be randomised measured by number and percentage of sites (drug services) | — |
Countries
United Kingdom
Outcome results
None listed