Surgery: Open abdominal aortic aneurysm repair Surgery Open abdominal aortic aneurysm repair
Conditions
Interventions
The technique of IPC temporarily reduces the blood flow to the patients legs in sequence for five minutes at a time. This causes the muscle in the patients legs to release various chemicals that can p
Sponsors
Record Provided by the NHSTCT Register - 2006 Update - Department of Health
Eligibility
Inclusion criteria
Inclusion criteria: Any patient scheduled to undergo elective infra-renal aneurysm repair will be eligible for inclusion. The following entry criteria with respect to renal function shall apply: 1. No history of acute renal failure 2. No history of renal replacement therapy (haemodialysis, haemofiltration, peritoneal dialysis) 3. No previous renal transplant 4. No previous renal disease 5. Serum creatinine less than 150 micromols/L at pre-operative assessment 6. Serum urea less than 20 mmols/L at pre operative assessment
Exclusion criteria
Exclusion criteria: 1. Patients with aneurysms above the level of the renal arteries have a very high risk of renal damage during surgery. These aneurysms are relatively uncommon. Their inclusion could bias the trial. 2. Patients with lower limb amputations will be excluded as they have less muscle in their lower limbs. Thus, the IPC stimulus could be inadequate and bias the trial results. 3. Patients with ankle-brachial pressure index < 0.7 will be excluded as the IPC technique could trigger acute lower limb ischaemia. 4. Patients who have undergone previous endovascular repair of the aneurysm will be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cardiac output measurement. | — |
Secondary
| Measure | Time frame |
|---|---|
| Not provided at time of registration | — |
Countries
United Kingdom
Outcome results
None listed