Poor ovarian response Pregnancy and Childbirth Fertility
Conditions
Interventions
Control group:
Thirty-five women underwent COH with a long GnRH agonist protocol: Triptorelin acetate SC (Decapeptyl® 0.1 mg, Ferring, Denmark) was administrated in the midluteal phase at a daily dos
Sponsors
Egyptian International Fertility and IVF Center (EIFC) (Eygpt)
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Women 20 - 42 years old 2. History of primary or secondary infertility (defined as the inability to conceive after 2 years of unprotected intercourse) 3. Normal menstrual cycle 4. Body mass index (BMI) less than 27 kg/m^2 5. Not taking medication for at least 1.5 months 6. Both ovaries are present 7. Basal FSH level on day 3 is less than 10 IU/L
Exclusion criteria
Exclusion criteria: 1. Clinically or medically significant systemic disease 2. Hypothalamic amenorrhoea 3. Cycle cancellation due to poor ovarian response; patients were defined as poor responders by number of dominant follicles on HCG day and number of mature oocytes less than 3
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Duration of stimulation (i.e. duration and amount of HMG used) 2. Consumption of gonadotrophins 3. Cycle cancellation rate 4. Number of mature follicles recruited 5. Total oocytes retrieved | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Laboratory outcomes 2. Implantation rate 3. Clinical pregnancy rates, 7 weeks from positive pregnancy test | — |
Countries
Egypt
Outcome results
None listed