Problematic use of illicit opiates requiring medical detoxification Mental and Behavioural Disorders Opioid dependence
Conditions
Interventions
Buprenorphine or methadone
Sponsors
University of Leeds (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Male or female, 18-65 years old, using illicit opiates as confirmed by a urine test at first assessment, remaining in the prison estate for longer than 28 days
Exclusion criteria
Exclusion criteria: Contraindications to buprenorphine or methadone, co-existing acute medical conditions requiring emergency admission to hospital so precluding detoxification in the prison setting, currently undergoing detoxification from other addictive drugs whereby concurrent detoxification from illicit opiates would not be clinically indicated, women who are pregnant or breastfeeding, prisoners previously randomised into this trial
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Abstinence of illicit opiates 5 days post completion of detoxification as indicated by a urine test | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse events recorded during the detoxification period: inappropriate use of prescribed medication, overdose, admission to prison healthcare, accident and emergency (A&E) or hospital. Abstinence at 1, 3 and 6 months post detoxification. At 1, 3 and 6 months: evidence and volume of service utilisation. | — |
Countries
England, United Kingdom
Outcome results
None listed